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diagnosis hematology differential folate mma nutrition aafp algorithm aplastic b1 comparison comparisontable encephalopathy folicacid korsakoff macrocytic macrocytosis management mds methylmalonicacid
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
Levels in Vitamin B12 ... • B12 Deficiency ... #B12 #MMA #folate ... #deficiency #VitaminB12 ... #diagnosis #hematology
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
conversion of homocysteine ... lead to elevated homocysteine ... Both homocysteine ... #VitaminB12 #Folate ... #Nutrition #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... deficiency is present ... deficiency. ... #VitaminB12 #Folate ... FolicAcid #MMA #Homocysteine
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Diseases: • Systemic lupus ... consumption • Vitamin B12 ... • Folate deficiency
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
form of Vitamin B12 ... an increase in homocysteine ... deficiency. ... of pernicious anemia ... #NitrousOxide #VitaminB12
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
thiamine (vitamin B1 ... ) deficiency, commonly ... and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... - Parvovirus B19 ... • Parvovirus B19 ... #oncology #hematology
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
Deficiency • Inadequate ... deficiency. ... autoantibodies (pernicious anemia ... #VitaminB12 #deficiency ... differential #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... or folic acid deficiency ... treatments • Copper deficiency ... Syndromes #diagnosis #hematology ... #oncology
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