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Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Worsening macrocytic anemia ... wt loss • If anemia ... to manifest its symptoms ... , alcohol use, symptoms ... - CBC, PBS - anemia
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... (B12, MMA) for ... diet/deficiency symptoms ... even if wnl B12
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Nutritional: vitamin B12
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
• Pernicious anemia ... /B12 deficiency ... mineralization Symptoms
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... • Thiamine B1 ... • Riboflavin B2 ... gestation • Vitamin B12 ... diagnosis #signs #symptoms
Medications for the Management of Anemia TREATMENT OF ANEMIA - Cyanocobalamin/B12 - Erythropoietin/epoetin alfa - Darbepoetin alfa
Management of Anemia ... TREATMENT OF ANEMIA ... Cyanocobalamin/B12 ... OF SICKLE CELL ANEMIA ... Pentoxifylline #Anemia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... - Anemia of chronic ... inflammation - Anemia ... disease - Vitamin B12
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, Signs and Symptoms ... of Hemolytic Anemia ... Pathophysiology #Hemolytic #Anemia ... diagnosis #signs #symptoms
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... and a vitamin B12 ... elevated, but anemia ... megaloblastic anemia ... that occur with B12
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin B12 ... Stomach: Pernicious anemia ... pylori infection, B12 ... BrighamChiefs #Vitamin #B12
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