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hematology management algorithm causes disorders oncology anemia cord nutrition signs spinal spinalcord symptoms syndromes weakness acidosis aplastic behcet bleeding cardiology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Wiskott-Aldrich syndrome ... Inflammatory and ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin ... Wernicke-Korsakoff syndrome ... #differential # ... diagnosis #signs
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... and Folate Deficiency ... #Causes #Hematology
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... cirrhosis, nephrotic syndrome ... , CNS Disease, Meds ... Glucocorticoid Deficiency ... #diagnosis #nephrology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
heavy metals), Critical ... Shellfish poisoning, Meds ... : Acid maltase deficiency ... Weakness #Causes #differential ... #diagnosis #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... endocrine: Vitamin B12 ... deficiency • ... #Diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... HIV) - Vitamin B12 ... , Copper deficiency ... #lesions #differential ... #diagnosis #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... Anemia #oncology #hematology ... #diagnosis #management
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
insufficiency, blind loops syndromes ... -IF complexes) and ... malabsorption syndromes ... #differential # ... diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
brain PRES Clinical ... may precede the neurologic ... Reversible course Differential ... Seizures: Treat with AEDs ... #neurology
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