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hematology oncology rash autoinflammatory bleeding canimorsus capnocytophaga cellulitis chronic cll cutaneous disorders e1 eschar history infection legs leukemia lymphocytic management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... Headaches • Pale skin ... #hematology #diagnosis
Staphylococcal Scalded Skin Syndrome (SSSS) A 5-year-old girl presents to the ED with a rash that started
Staphylococcal Scalded Skin ... Syndrome (SSSS) ... #Clinical #Photo ... #Peds #Pediatrics ... #Dermatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... nose chondritis, skin ... Abnormalities: macrocytic anemia ... myeloid cells NEJM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... just beneath the skin ... • Aplastic Anemia ... Nutritional: vitamin B12 ... #diagnosis #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
hemochromatosis, hemolytic anemia ... immunosuppressive meds ... rash #cellulitis #dermatology ... #legs #clinical ... #photo
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... • Neutropenia, anemia ... Pure red cell aplasia ... • Richter’s Syndrome
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... persist → DIC, MODS ... the key to the diagnosis ... #Rash #dermatology ... #clinical #photo
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... , SLE, trauma, aplastic ... anemia & steroid ... #skin #clinical ... #photo
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... membrane bleeding and skin ... Marfan syndrome, ... Disorders #History #peds ... #pediatrics #diagnosis
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