7 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Pernicious anemia/B12 ... respiratory failure • Neurologic ... loss of teeth • Muscular ... Phosphatase: • Other causes
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Alzheimer - 1st cause ... (parkinsonian signs ... - Behavioral changes ... Loss of bladder control ... #Geriatrics #Workup
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... lesions of the central ... endocrine: Vitamin B12 ... Lack of UMN/LMN signs ... Lack of sensory changes
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... infectious disease caused ... Romana's sign ... Indeterminate form (No signs ... 90-120 days • Pediatric
Pediatrics Sepsis Screening
SIGNS OF INFECTION?
 • Fever (>38C)
 • Hypothermia (<36C)
 • Cough/chest pain/respiratory distress
 •
Pediatrics Sepsis ... • Indwelling vascular ... extremities) • Mental ... status changes ... #peds #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Seizures • Vision changes ... may precede the neurologic ... the underlying cause ... until cause identified ... #management #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... affects the skin, neurologic ... Angiitis of the Central ... and gray matter changes ... tract, and often causes