32 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Osteomyelitis / Septic Arthritis ... #differential # ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
) - MSK Radiology ... mass and NO prior signs ... Differential diagnosis ... diffuse chondral disease ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... Joint #pain #Differential ... #Diagnosis #MSK
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... Fever/Chills/Joint ... #differential # ... diagnosis #msk #
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Legg-Calve-Perthes disease ... Neuropathy (DM, Vit B12 ... - HIV - Lyme disease ... lower #extremity #msk
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... Veno-occlusive disease ... #Diagnosis #causes ... #hepatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... oral ulcers in 12 ... ) Differential Diagnosis ... , AS Treatment: ... diagnosis #management #signs
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... nonerosive inflammatory arthritis ... Rule out other causes ... and lower jaw Treatment ... osteoarticular and skin disease
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... surfaces of the joints ... reticularis Differential ... • Giant cell arteritis