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diagnosis infections management opportunistic anthracycline capsulatum cardiotoxicity chemotherapy cns differential fungal her2 histoplasma histoplasmosis hiv hivaids idsa mycoses oncology prevention
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Infection in HIV / AIDS ... Antimicrobial treatment ... Demyelinating disease ... caused by the JC ... opportunistic #InfectiousDiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Infections in HIV-AIDS ... Severe Disseminated Disease ... BID for at least 12 ... IDSA #Prevention #Treatment ... infections #HIVAIDS #pharmacology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... duration is 6 to 12 ... extrapulmonary disease ... yeast • At risk: AIDS ... ) #Mycoses #InfectiousDiseases
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... HER2 agents cause ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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