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diagnosis hematology differential management syndrome acidosis acute anthracycline aplastic cardiotoxicity chemotherapy chronic classification cll elevation endocarditis her2 hiv infectiousdiseases lactate
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Nutritional: vitamin B12 ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... perfusion - shock->treatments ... before beginning treatment ... of Circulatory System ... 30mmHg) - Severe anemia
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Central nervous system ... enzymes ↑ • Mild anemia ... • New onset SLE ... detecting HIV for 10-12 ... antibody test) Treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
• Autoimmune (SLE ... Septic emboli cause ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Differential #Diagnosis #cardiology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... ) and initiate treatment ... renin-angiotensin-aldosterone system ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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