21 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Small Bowel ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... - Parvovirus B19 ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... diagnosis #hematology #oncology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... wt loss • If anemia ... to IBD, celiac disease ... Check for IF ab Treatment
Ileal Pouch Disorders - Differential Diagnosis
 • Surgical/Mechanical: Anastomotic leak, Pelvic sepsis, Sinus, Fistula, Strictures, Efferent
Cuffitis, Crohn's disease ... Small bowel bacterial ... Systemic/Metabolic: Anemia ... Bone loss, Vit D/B12 ... Diagnosis #surgery #gastroenterology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Fever Hematologic disease ... caused by Bartonella ... Incubation period: 3-12 ... severe hemolytic anemia ... TREATMENT: ​• Acute
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
HCO3)} Normal = 12 ... D-lactate (short bowel ... syndrome, intestinal ... Renal failure (uremia ... restrictive lung disease
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
presentations and disease ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... Clinical Manifestations ... Treatment: • ... Baclofen • Severe Disease
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology