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hematology oncology management differential lymphoma syndromes cell chronic classification cll hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis mds myelodysplasia myelodysplastic nonhodgkins plasmacytoma
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Lymphoma - Comparison ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... lymph node biopsy (diagnostic ... Lymphoma Treatment ... #lymphoma #diagnosis ... classification #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... identical to the non-Hodgkin ... microglobulin Treatment ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Hemopathies+++: Hodgkin ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... mononeuritis multiplex WORKUP ... & DIAGNOSIS Labs ... capillaritis leading ... #management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... are caused by bleeding ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... EMD myeloma Diagnostic ... Bone marrow Treatment ... macroglobulinemia • Non-Hodgkin ... #Workup #Hematology
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