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diagnosis management differential activetb anticoagulation doac latenttb leukemia malignancy tb tuberculosis vte anemia aplastic apml cardiology causes chf clinical cll
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... thrombosis in cancer ... at high risk of bleeding ... #Management #Hematology ... #Oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... thrombosis; PE = pulmonary ... #Management #Hematology ... #Oncology
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 Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Leukemia - History of Bleeding ... Age > 50 • Chronic ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... • Spontaneous bleeding ... neutrophil count < 500 cells ... differential #diagnosis #cancer
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
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