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diagnosis hematology management blood product reactions rheumatology algorithm dermatologic gpa granulomatosis infections infectiousdiseases leukemia mds mycobacteria myelodysplasia myelodysplastic nonpalpable nontuberculous
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... and petechiae Causes ... #Anemia #oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... cryoglobulins • Skin ... #Differential # ... #dermatology #physicalexam
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Petechiae, Palpable ... Maculopapular rash ... reticularis Differential ... #rash #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... Vasculopathy #Purpura #Differential ... #nonpalpable #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... by bleeding (petechiae ... • Anemia • Aplastic ... blood count with differential ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Causes purpura & ... due to marrow aplasia ... coagulopathy & ↑bleeding ... infections with skin
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Causes purpura & ... due to marrow aplasia ... coagulopathy & ↑bleeding ... infections with skin
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... other RGM • Plastic ... bloodstream - seeding ... Bone Marrow - Anemia ... NTM #Infections #differential
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