14 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... changes), high MCV anemia ... vegan, gastric bypass ... #Workup #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... cause temporary ... #hepatology #diagnosis ... #gastroenterology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(MAS) Classified ... purpura to mucosal bleeding ... with leukopenia, anemia ... ↑ AST ↑ ALT ↑ bilirubin ... Diagnosis #Management #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... and petechiae Causes ... Constitutional Syndromes ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... unusual bruising or bleeding ... by bleeding (petechiae ... Out Secondary Causes ... #diagnosis #hematology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Consider refeeding syndrome ... deficiencies) Dumping Syndrome ... causes increased ... and Hepatology ... #gastroenterology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
system: 1st ... : • Mast cell ... activation syndrome ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... synthetic function may ... • Gilbert's syndrome ... RBC (hemolysis, bleeding
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... -> AML: Blast crises ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology