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management leukemia product reactions anemia causes chronic classification cll differential disorders hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic platelet syndromes thrombocytopenia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... ecchymoses, mucosal bleeding ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... - History of bleeding ... plateletcount), peripheral blood ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Causes • Anemia • Aplastic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... #workup #oncology ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... : • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
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