12 results
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... hemolytic #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Petechiae on Physical Exam

Pinpoint, round spots that appear on the skin as a result of microscopic
as a result of microscopic ... bleeding #Petechiae ... #PhysicalExam #dermatology ... #foot #skin #clinical ... #video
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's sign is a clinical ... differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... purpura to mucosal bleeding ... #Diagnosis #Management ... #Hematology #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... abnormal under the microscope ... abnormal under a microscope ... #diagnosis #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... : • + Clinical ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... Anemia #oncology #hematology ... #diagnosis #management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... : • Clinical triad ... Labs/Diagnosis: ... vasculitis - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis