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Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... non-specific red cell ... polychromatophilic cells ... #Hematology #Pathology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... Lymphomas • Other hematologic ... #differential #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... ecchymoses, mucosal bleeding ... - CMV - HCV ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... anemia • Cold ... Mycoplasma, EBV, HIV ... sensitize red blood cells ... #hematology #diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... autoimmune hemolytic anemia ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... occlusions, as well ... : • + Clinical ... Biopsy: Typical pathologic ... hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
cell counts less ... Hematologic malignancy ... Bone Marrow - Anemia ... Pulmonary Disease: Clinical ... Lung Disease: • Clinical
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... Diagnosis? ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... #Workup #Hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
median age at diagnosis ... disease tolerate anemia ... with repeated red cell ... an infection or bleeding ... #algorithm #hematology