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diagnosis oncology management activation aplastic causes differential disorders leukemia macrophage mas mds myelodysplasia myelodysplastic platelet rheumatology syndrome syndromes thrombocytopenia workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... (petechiae, ecchymoses ... plateletcount), peripheral blood ... changes), high MCV anemia ... Causes #Workup #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... ecchymoses, mucosal bleeding ... , and petechiae ... result from low blood ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... Significant ↓ PLT: Petechiae ... - infiltrates (anemia ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... Syndromes #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... with leukopenia, anemia ... Diagnosis #Management #Hematology
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