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management leukemia product reactions anemia chronic cll criteria enterocolitis lymphocytic mds myelodysplasia myelodysplastic nec neutropenic syndromes transfusion transfusions workup
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Diagnostic criteria ... Diarrhea • Lower Gl bleeding ... Enterocolitis #Diagnosis ... #criteria #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... ecchymoses, mucosal bleeding ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... , weight loss, abdominal ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Causes • Anemia • Aplastic ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... #workup #oncology ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Injury (TRALI): Leading ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
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