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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood ... disorders. ... #disorders #leukemia ... #hematology #oncology ... #CLL #AML #Map
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Acute • Myloid (AML ... - Myelodysplastic ... @AmyChung #Blood ... #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... the peripheral blood ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... transformation to AML ... • Hairy Cell Leukemia ... progression to AML ... Syndromes #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Chronic inflammatory disorders ... vera (PV) • Myelodysplastic ... Chronic myeloid leukemia ... (CML) - Dr. ... Diagnosis #Causes #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Myeloproliferative Disorders ... Chronic myeloid leukemia ... (CML) - associated ... Diagnosis #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... not required in all ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... Transform to DLBCL, PML ... workup #oncology #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... • Hypocellular myelodysplastic ... virus (EBV) • Leukemia ... result from low blood ... Anemia #oncology #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic ... acute myeloid leukemia ... (AML). ... an infection or bleeding ... #algorithm #hematology