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diagnosis oncology management skin agglutinin angioma bandemia blanching cbc cellulitis chronic classification cll cold common cvid differential erythematosus hemolytic hodgkins
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... can indicate disease ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... hemolysis • C3↓ C4 ... sensitize red blood cells ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Pinpoint-sized red spots ... Myeloproliferative Disease ... Workup: • Complete ... Syndromes #diagnosis #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
cellulitis w/ black spots ... chronic liver disease ... hemochromatosis, hemolytic anemia ... rash #cellulitis #dermatology ... #legs #clinical
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... autoimmune hemolytic anemia ... unless levels are less ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... lymphopenia, low PLT • Anemia ... levels (C3 and C4 ... activity • C3 C4 ... : • Chronic B-cell
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Left Shift: • Cell ... precursors" • Stab cell ... • Autoimmune diseases ... neutrophil #WBC #CBC #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • Scapula • Less ... • No CRAB - no anemia ... Oncology #Diagnosis #Workup ... #Hematology
Blanching Spider Angioma (Nevus) on Physical Exam Spider angiomas are usually benign but often can be suggestive
underlying systemic disease ... a central, red spot ... features: a body, legs ... #clinical #video ... #dermatology #skin
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