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systemic pruritus allergy alopecia focal gap globulin hairloss immunology lupus lymphocytic mds myelodysplasia myelodysplastic pathergy primary protein proteingap rheumatology sle
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Diagnosis Algorithm ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... #CLL #Chronic ... #diagnosis #workup ... #oncology #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... to Skin Disease ... HairLoss #Alopecia #dermatology ... Diagnosis #Algorithm ... #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Frank nephritis (hypertension ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Causes • Anemia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Skin trauma → Erythematous ... • Chronic myeloid ... leukemia (CML) ... #differential # ... allergy #immunology #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
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