5 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... or lymphoid malignancy ... - Lymphoid Malignancy ... younger pts) Differential ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Agglutination - Cold ... Consider RBC membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphoma • Evans ... the context of primary ... Frank nephritis (hypertension ... #Diagnosis #Rheumatology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Biopsy: Solitary disorder ... except for the primary ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology