4 results
anemia hemolytic bandemia monoclonal neutrophil paraproteinemias testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease ... Blood smear - RBC ... malignancies - B-cell ... malignancies -> CLL ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Consider sickle cell ... agglutinins disease ... #Diagnosis #Algorithm ... #workup #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... relative to both WBC ... 21% had normal WBC ... #WBC #CBC #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... +Organomegaly+↑RBC ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
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