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chronic lymphocytic classification erythematosus hemeonc hemolytic monoclonal neutrophil paraproteinemias plasmacytoma rheumatology sle solitary systemic testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... , Hodgkin’s lymphoma ... #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... Consider sickle cell ... Diagnosis #Algorithm ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... platelets - WBC ... classification #hematology ... #oncology #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Left Shift: • Cell ... precursors" • Stab cell ... relative to both WBC ... #WBC #CBC #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Angioimmunoblastic T-cell ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... : • Chronic B-cell ... lymphoma and leukemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... +Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
MM, the plasma cell ... • No CRAB - no anemia ... • CBC + diff • ... #Diagnosis #Workup ... #Hematology
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