3 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease ... Agglutinin Syndrome ... Blood smear - RBC ... Diagnosis Monoclonal ... #hematology #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... #Gap #ProteinGap ... diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Protein/M Component ... +Organomegaly+↑RBC ... due to cold IgG ... Paraproteinemias #Hematology ... #Monoclonal #Differential