18 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... marrow • Mature B-cell ... involvement • T-cell ... - infiltrates (anemia ... form of large cell
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... and other C Cell ... AIHA • Pure red cell ... lymphoma • Hairy cell ... Smoldering adult T cell
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Sickled red cells ... : Sickle cell disease ... Bite cells: G6PD ... Analysis #hematology #microscopy
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #Body #Bodies #Pathology ... #Hematology #Smear ... #Clinical #Microscopy
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
non-specific red cell ... polychromatophilic cells ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... low white blood cell ... hematopoiesis cell ... or three blood cell ... or more blood cell
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell ... leukemia Genevieve ... formation #Clinical #Smear ... #Hematology #Pathology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
required for dx - T-cells ... mature cytotoxic T-cell ... chronic LPD of NK cells ... clinical disease but cells ... are NK cells (sCD3
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... • Peripheral smear ... lymphocytes, smudge cells ... Transformation to large cell ... uw_IMresidency #CLL