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diagnosis differential aids hematology hiv infectiousdiseases leukemia lung management neurology oncology renal rheumatology treatment vasculitis weakness
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... Other tests: • CT ... confirm DAH, r/o infection ... recent DAN) • EMG/NCS ... seen on chest CT
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... etc) • CNS -> ... PNS -> NMJ -> Muscle ... Coxsackie, HIV, CMV, EBV ... cryoglobulins • PNS
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... involvement • 30%: CNS ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... pain and GN Anti-GBM ... , recent viral infection ... chorioretinitis, CNS ... vasculitis • Cogan syndrome
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 syndromes ... • CT: Halo sign ... Lymphadenopathy, CNS ... #HIV #AIDS #pulmonary
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