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oncology syndrome activation anemia antinxp2 antinxp2dm aplastic arteritis cdiff chronic classification cll clostridioides clostridium dermatology dermatomyositis differential difficile disease gastroenterology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Acute Diarrhea (>3 BM ... Epidemiology: • #1 ... equivocal • CT ... 10 mg/kg IV x 1 ... #management #treatment
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... concentration PET-CT ... conventional imaging (aorta ... #management #phenotypes ... #rheumatology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... Methylprednisolone (MP) 1 ... #Neuritis #Diagnosis ... #Management #treatment ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Waiting" →several RCTs ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Auto-amplification loop Diagnosis ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL-1 ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... in literature (NEJM ... Treatment of GCA ... them, but urgent rheumatology ... #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Hematologic: ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
F • 3 peaks: 1) ... Toxic injury to BM ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
B symptoms in 1/ ... Mediastinal mass) • CT ... physical exam, CT ... classification #hematology ... #oncology #management
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