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management differential oncology anemia classification vasculitis activation agglutinin aplastic arteritis autoimmune cdiff chronic cll clostridioides clostridium cold difficile disease gap
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Acute Diarrhea (>3 BM ... Epidemiology: • #1 ... equivocal • CT ... 10 mg/kg IV x 1 ... Treatment Guideline
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL-1 ... nervous system (CNS ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
F • 3 peaks: 1) ... Constitutional Syndromes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Antibodies: 1. ... Cold Agglutinin Syndrome ... - Mycoplasma, EBV ... hemolytic #anemia #hematology ... #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... Hematologic: ... Adenocarcinoma Treatment ... #Rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... in literature (NEJM ... cases (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
surface molecules: CD5 ... CLL Labs: 1. ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... glomerulonephritis) • Anti-GBM ... • Cogan Syndrome ... • ANA (Suggest CTD ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
B symptoms in 1/ ... Mediastinal mass) • CT ... physical exam, CT ... Hodgkin Lymphoma Treatment ... classification #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... < 30 years • Aorta ... Arteritis): • Aorta ... pain and GN Anti-GBM ... #Rheumatology
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