928 results
Cardiac Myocyte Contractile cycle
 - Ca2+ binds to TnC → TnI is inhibited → conformational change
site between actin ... interact with active ... sites on actin ... ” myosin along actin ... to inhibit the action
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Diuretics #Sites #Action
VA ECMO Unloading - LV Venting
Different LV Venting Strategies work through these basic mechanisms: ↓ Preload,
Contractility, ↓ Afterload ... Vasodilators: ↓ Afterload ... Reducing ECMO Flow: ↓ Afterload ... • IABP: ↓ Afterload
Mean Arterial Pressure (MAP)

Average arterial pressure throughout one cardiac cycle, systole, and diastole. 
Surrogate indicator of
Afterload also affects ... an increase in afterload ... affected by the chronotropy ... #afterload #Heartrate ... #chronotropy #dromotropy
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
: No effect • Chronotropy ... Inotropy: Decrease • Chronotropy
Cardiac Maneuvers and Effects on Murmurs

Valsalva Standing - Decr BIood Return to LV
Laying Down, Squatting, Straight
Phenylephrine - Incr Afterload ... Nitrate - Decr Afterload ... Post PVC - Decr Afterload
Hormones acting on the kidney - Nephron map

#Hormones #Nephron #Sites #Action #Pathophysiology #Nephrology #Renal #Kidney
Hormones acting ... Nephron #Sites #Action
Hormones acting on the kidney

#Pathophysiology #Nephrology #Renal #Kidney #Hormones #Nephron #Sites #Action

** GrepMed Recommended Text: First
Hormones acting ... Nephron #Sites #Action
Insulin Pharmacology and Conversion

 • Conversion of U-100 to U-500 Insulin
 • Inpatient Intravenous to subcutaneous
• Duration of Action ... and Intermediate Acting ... • Duration of Action ... : Long Acting Insulins
The Death Spiral: Increased RV Afterload (Acute PE) 
#Pathophysiology #PE #PulmonaryEmbolism #Embolism #DeathSpiral #Shock #RVDysfunction #RebelEM
: Increased RV Afterload