22 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... Hypokalemia Metabolic alkalosis ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... - Differential Diagnosis ... , Gitelman Syndrome ... #Differential #Diagnosis ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential Diagnosis ... , Gitelman Syndrome ... #Differential #Diagnosis ... #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... tubule (DCT) Clinical ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic Alkalosis ... : Differential Diagnosis ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology ... #differential #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
↓ Aldosterone: Syndrome ... - Metabolic Alkalosis ... , Gitelman syndrome ... #Hypokalemia #diagnosis ... differential #potassium #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... - Differential Diagnosis ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... #Differential #Diagnosis
Clinical Manifestations of Gitelman Syndrome #Diagnosis #Nephrology #Gitelman #Syndrome #Manifestations #Symptoms
Clinical Manifestations ... of Gitelman Syndrome ... #Diagnosis #Nephrology ... #Gitelman #Syndrome
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag Syndrome ... Purple #Urine #Bag #Syndrome ... #PUBS #pathophysiology ... #clinical #photo ... #differential #diagnosis