7 results
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... Antibiotics Class Overview ... vs Candida -> Drug ... Echinocandins lack activity ... Anidulafungin #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... intracellular rod-shaped bacteria ... inhibitors • Injection drug ... Active: Symptomatic ... Response: • Most bacteria
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... intracellular rod-shaped bacteria ... inhibitors • Injection drug ... Active: Symptomatic ... Response: • Most bacteria
For my UME micro course, I made a figure that captures this terminology and lets learners
clinically important bacteria ... antibiotic, it would ... contrast important drug ... common beta lactam drugs ... #antibiogram #pharmacology
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Antibiotics Class Overview ... BACTRIM/SEPTRA ... other agents are: activity ... including PCP PNA (drug ... #Pharmacology #Antibiotics
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis ... no evidence of active ... latent TB • Close ... Mycobacterium #Tuberculosis ... infections #HIVAIDS #pharmacology
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
beta-lactam allergy (has activity ... beta-lactam allergy would ... Chloramphenicol +/- Bactrim ... several weeks after drug ... #Pharmacology #Antibiotics