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diagnosis differential rheumatology types vasculitis allergy hypersensitivity reactions comparison cryoglobulinemia cryoglobulins hematology hypocomplementemia low mnemonic pathophysiology progressive rapidly rpgn vasculitides
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement ... #CHAMPS #Mnemonic
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Complement activation ... Post-streptococcal glomerulonephritis ... , and systemic lupus ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... • Low serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
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