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diagnosis management differential causes treatment nephrology cardiology endocrinology peds hematology symptoms pulmonary ddxof signs workup gastroenterology pediatrics neurology syndrome evaluation
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test T-1m: Baseline cortisol drawn T0: 250 µg cosyntropin given IV T30m: Repeat
Insufficiency Algorithm ... T-1m: Baseline cortisol ... IV T30m: Repeat cortisol ... drawn T60m: Final cortisol ... Insufficiency #Testing #Algorithm
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Syndrome Testing Algorithm ... Free Urine • Cortisol ... following morning: Cortisol ... , Serum (or Cortisol ... Syndrome #diagnosis #algorithm
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... This means cortisol ... stimulation, thus low cortisol ... Insufficiency #Pathophysiology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... ACTH Early am cortisol ... Cosyntropin - Measure cortisol ... injection - If f/u cortisol ... Insufficiency #Diagnosis #Algorithm
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... Screening Test: 6-8AM Cortisol ... Early morning cortisol ... - Peak cortisol ... Insufficiency #Algorithm
Nephron Physiology and Transporters • Proximal Tubule • Thick Ascending Limb • Distal Convoluted Tubule •
Convoluted Tubule • Cortical ... Duct #Nephron #pathophysiology
Adrenal Insufficiency Diagnosis Algorithm Clinical features: - Weight loss, anorexia, Weakness, fatigue, GI distress - Hypotension,
Insufficiency Diagnosis Algorithm ... findings (see algorithm ... : - AM serum cortisol ... unlikely - If serum cortisol ... Insufficiency #Diagnosis #Algorithm
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm Not the "classic" Volume based approach. #Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Hyponatremia - Diagnostic Algorithm ... #Hyponatremia #Algorithm ... #Pathophysiology
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Consider: SIADH, Cortisol ... #differential #algorithm
Polycythemia (Erythrocytosis) - Pathophysiology #Polycythemia #Erythrocytosis #Pathophysiology #hematology #algorithm #differential #diagnosis
Erythrocytosis) - Pathophysiology ... Erythrocytosis #Pathophysiology ... #hematology #algorithm
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