6 results
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the evaluation ... RBC = red blood cell ... by ordering a peripheral ... #Diagnosis #Macrocytosis ... FolicAcid #MMA #Homocysteine
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... cytometry • Peripheral ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... immature RBCs) in peripheral ... High in acute blood ... #Workup #Hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
tongue), abd pain, diarrhea ... total body stores Evaluation ... findings, HSM, LN, peripheral ... Elevated MMA and homocysteine ... consider other diagnosis
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
ridging around the periphery ... Diagnosis? ... • No CRAB - no anemia ... Evaluation? ... #Workup #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... myeloma • Plasma cell ... anemia • Other ... #differential #diagnosis