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hematology differential algorithm causes leukemia macrocytic aafp cell chronic disorders folate folicacid gap globulin homocysteine hospitalization lymphocytic macrocytosis mds microcytic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cytometry • Peripheral ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... by ordering a peripheral ... of the initial work-up ... #Diagnosis #Macrocytosis ... Homocysteine #Algorithm #Workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... immature RBCs) in peripheral ... High in acute blood ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... plateletcount), peripheral ... changes), high MCV anemia ... - Bone marrow evaluation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... bone marrow and peripheral ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... blood loss or acute ... of unnecessary diagnostic ... #differential #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
ridging around the periphery ... • No CRAB - no anemia ... Evaluation? ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... anemia • Other ... inflammation (acute ... #differential #diagnosis
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