34 results
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver Disease ... (Cirrhosis) - Complications ... Hepatocellular Carcinoma (HCC ... Complications #diagnosis #management ... #summary #hepatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Primary biliary cirrhosis ... (PBC) Anticentromere ... Anti-Scl-70 - Scleroderma ... diagnosis #table #rheumatology ... #antibodies
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... [PCH] 3. ... Cold Agglutinin Syndrome ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH ... , Evans Syndrome ... , Drugs, Liver Disease ... Electrolytes: Wilson's disease ... Differential #Diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome ... #treatment #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Miller Fischer and PCB ... Labs: - AchR antibodies ... assay - MuSK antibodies ... - LRP4 antibodies ... Gravis #diagnosis #management
Lyme Disease - Diagnosis and Management Summary

Lyme Disease Epidemiology:
- Spirochete
- Reservoir: small mammals & birds
- Transmitted
and Management ... Detects antibodies ... Treatment: 1. ... cefotaxime or PCN ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... smear negative, PCR ... trypomastigotes) 2) PCR ... to detect IgG antibodies ... Trypanosomiasis #Diagnosis #Management