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differential hematology symptoms vasculitis arthritis behcet classification disease gap globulin monoclonal oncology paraproteinemias polychondritis protein proteingap relapsing rheumatoid sjogrens vasculitides
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... Hypergammaglobulinemic macular ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... : Giant retinal ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
and Symptoms • Ocular ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... Rheumatoid #Arthritis #RA ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... Differential Diagnosis ... purpura: strong sign ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... Diagnosis: • Dry ... gland) biopsy • Ocular ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... Vasculitis Differential Diagnosis ... purpura: Strong sign ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
chondritis • Ocular ... as: • SLE • RA ... Diagnosis: ... Polychondritis #rheumatology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... changes (POEMS syndrome ... tissue disorders (RA ... cancers, HCC, renal ... #differential #diagnosis
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