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diagnosis management neurology syndrome pediatrics vertigo algorithm als amyotrophic causes central childhood crisis dizziness encephalopathy genetics gitelman hypokalemia immunization lateral
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... fractures • Short ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Diagnostic Algorithm for Dizziness and Vertigo Peripheral Vertigo: • Attacks: Sudden, severe, can last anywhere from seconds
findings BPPV • Short-lived ... No auditory symptoms ... Long symptom-free ... Vertigo #Algorithm #differential ... #diagnosis #neurology
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
vertigo (BPPV) - Short-lived ... Long symptom-free ... Positional symptoms ... Vertigo #Causes #differential ... #diagnosis #neurology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... #Immunization #peds ... #pediatrics #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... Seizures: Treat with AEDs ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... diagnosis #management #neurology ... #differential
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
anemia (MAHA) Pathophysiology ... Initiate ACEi (short-acting ... , add other BP meds ... #rheumatology #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypocalciuria (spot ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
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