12 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Trauma, Tumor • Motor ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis ... #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
muscle weakness ... sensory symptoms or signs ... , Cranial nerve ... nervous system signs ... #neurology #neuropathy
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Diagnosis: • ... #diagnosis #management ... #treatment #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... Upper Motor Neuron ... Lack of UMN/LMN signs ... #Differential #Diagnosis ... #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Complications: • Weakness ... damage to sacral nerves ... #MSK #pathophysiology ... #diagnosis #symptoms
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... SinaiBmoreIMRes #GBS #Guillain ... #Barre #Syndrome ... #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Disease of motor ... activity between nerve ... cells and motor ... Lateral #Sclerosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Brain stem/Cranial nerve ... test - Cogan sign ... - Peek sign ... - Repetitive nerve ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... : • Sensory, motor ... • Bilateral signs ... brain and/or optic nerve ... #management #neurology