18 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Diagnosis: • ... #diagnosis #management ... #treatment #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
muscle weakness ... sensory symptoms or signs ... , Cranial nerve ... nervous system signs ... #neurology #neuropathy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tumor • Motor Nerves ... Poliomyelitis, Guillain-Barre ... #differential #diagnosis ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Barre #Syndrome ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... Lack of UMN/LMN signs ... #Differential #Diagnosis ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Brain stem/Cranial nerve ... test - Cogan sign ... - Peek sign ... - Repetitive nerve ... #management #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... anesthesia. leg weakness ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Floppy Baby Syndrome
 • Infantile Botulism
 • Acute Flaccid Myelitis
 • Guillain Barre
 • Neonatal Myasthenia
Flaccid Myelitis • Guillain ... resistance - Weakness ... perinatal history is crucial ... LMN signs - Assess ... #differential #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Complications: • Weakness ... damage to sacral nerves ... #MSK #pathophysiology ... #diagnosis #symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Spasm, Cramping, Weakness ... vision, Diplopia, Weakness ... #management #neurology ... #treatment #MS