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diagnosis causes differential infections fungal infectiousdiseases comparison betadglucan biomarkers cns fungi fungus galactomannan lesions management microbiology mycoses neurology radiology ringenhancing
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
exceptions are Aspergillus ... polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... #microbiology #microscopy
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... Mucormycosis, Cryptococcus ... #Lung #Infections
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Mucormycosis, Cryptococcus ... @ID_fellows #Brain ... #Lung #Infections
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Beta-D-Glucan and Aspergillus ... - Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... decreased with: concurrent ... Clav (may be + as long
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... , and aspergillus ... RingEnhancing #Lesions #Brain
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fluconazole CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... ASPERGILLOSIS • Aspergillus ... • Sinusitis • Brain
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