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Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... vessels involved/damaged ... systemic sx + signs ... in literature (NEJM ... #Temporal #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... Elevated ESR and CRP GCA ... develop in pts with GCA ... • Progressive symptoms ... (PR3-ANCA)): Microscopic