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diagnosis differential algorithm bleeding bruising gap globulin hemophagocytic hlh lymphohistiocytosis management protein proteingap summary treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
disrupts immune homeostasis ... B-LNH), solid cancers ... Drugs, Unknown cause ... inhibitors under evaluation ... treatment #summary #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Disorders of Hemostasis ... • Warfarin • Acute ... discern these causes ... Liver disease • Acute ... Differential #Diagnosis #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
first step in evaluation ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
From Blood Cancer ... risk of clonal evolution ... to acute myeloid ... cardiovascular or pulmonary ... #algorithm #hematology
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