17 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... : fever +++, hepatosplenomegaly ... inhibitors under evaluation ... #management #treatment ... #summary #rheumatology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... active ROM +/- fever ... necrosis, Lyme disease ... count, and crystal evaluation ... MH/CCF/CWRU EM
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
and Management ... Summary Acute Chagas ... Mild: Malaise, fever ... Acute myocarditis ... detectable by blood
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - Clinical ... Acute phase ... - Recurrent disease ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... ) B symptoms → fevers ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... cells can indicate disease ... ’s lymphoma or acute ... #workup #oncology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... of peripheral blood ... • Autoimmune diseases ... tachycardia or fever ... count on initial evaluation
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... S/sx: Fever, flank ... Transfusion Related Acute ... #Transfusion #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management