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lupus systemic summary activation allergic aspergillosis bronchopulmonary classification comparison criteria druginduced eularacr hematology hemophagocytic hlh lymphohistiocytosis macrophage mas pulmonary syndrome
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... of SLE • Evolution ... #Diagnosis #Management ... #Summary #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... weight loss, and fever ... Classification: • Acute ... Differential Diagnosis ... #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... Constitutional domain: Fever ... discoid lupus, Acute ... Classification #Criteria #SLE ... #diagnosis #rheumatology
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
WHAT ARE THE CLINICAL ... • Low grade fever ... ON LABORATORY EVALUATION ... #pulmonary #diagnosis ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Systemic Lupus Erythematosus ... of SLE • Evolution ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: fever +++, hepatosplenomegaly ... Autoimmune diseases: SLE ... inhibitors under evaluation ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
is the main clinical ... [SLE], AOSD) • ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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