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diagnosis rheumatology differential joint msk calcium cppd gap globulin laboratory management protein proteingap pseudogout pyrophosphate rheumatic rheumatoid testing
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... Crystal Deposition ... : • Acute or chronic ... #MSK #rheumatology ... #approach #workup
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... ), RA, crystal disease ... #rheumatology # ... approach #workup
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... Pyrophosphate Deposition ... onset of swelling, pain ... neck pain, fever ... #Disease #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Acute ... profile, including liver ... , and low back pain ... #laboratory #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... Sarcoidosis) • Liver ... inflammation (acute
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