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diagnosis rheumatology cppd differential management approach blood calcium comparison gap globulin gout joint laboratory msk protein proteingap pseudogout pyrophosphate reactions
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Crystal Deposition ... : • Acute or chronic ... ochronosis and crystal deposition ... #MSK #rheumatology ... #approach #workup
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... Pyrophosphate Deposition ... Pyrophosphate produced ... neck pain, fever ... #Disease #Rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Pyrophosphate produced ... onset of swelling, pain ... Monosodium urate deposition ... swelling, significant pain
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Acute ... profile, including liver ... , and low back pain ... #laboratory #workup
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
One Pager Summary ... - Acute Hemolytic ... : Fever, flank pain ... eruptions, diarrhea, liver ... diagnosis #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... Sarcoidosis) • Liver ... inflammation (acute
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