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diagnosis rheumatology arthritis chronic differential sle algorithm approach cll comparison diarrhea druginduced erythematosus hemophagocytic hlh joint laboratory leukemia lymphocytic lymphohistiocytosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... • Immunologic Workup ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... : Chronic disease ... #diagnosis #management
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the Evaluation ... Causes of acute ... Systemic disease ... leukocytes and occult blood ... #algorithm #workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... Noninflammatory • Bloody ... tumor • Non-bloody ... #approach #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... cells can indicate disease ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... #oncology #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... Screening Tests for Acute ... Polyarthritis: • Blood ... : • Complete blood
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
One Pager Summary ... - Acute Hemolytic ... Transfusion Related Acute ... Transfusions #diagnosis #management ... #hematology #reactions
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... Summary WHAT ... presents with an acute ... • An evaluation ... #Rheumatology
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