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rheumatology management hematology druginduced erythematosus activation chronic cll comparison differential dil disease gap laboratory leukemia lymphocytic macrophage mas oncology protein
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... #lupus #Systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... #Systemic #Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... [SLE], AOSD) • ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... the presence of anemia ... Screening Tests for Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... increase in gamma globulins ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... #rheumatology #diagnosis ... #treatment #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... Thalassemia, Sickle cell anemia ... #differential #diagnosis
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